Comparative testicular transcriptome of wild type and globozoospermic Dpy19l2 knock out mice
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چکیده
منابع مشابه
Comparative testicular transcriptome of wild type and globozoospermic Dpy19l2 knock out mice
BACKGROUND Globozoospermia is a male infertility phenotype characterized by the presence in the ejaculate of near 100% acrosomeless round-headed spermatozoa with normal chromosomal content. Following intracytoplasmic sperm injection (ICSI) these spermatozoa give a poor fertilization rate and embryonic development. We showed previously that most patients have a 200 kb homozygous deletion, which ...
متن کاملCorrection: Dynamics of Sun5 Localization during Spermatogenesis in Wild Type and Dpy19l2 Knock-Out Mice Indicates That Sun5 Is Not Involved in Acrosome Attachment to the Nuclear Envelope
There is an error in the third author’s name. The correct surname for the third author is: Abi Nahed. The correct given name is: Roland. The correct citation is: Yassine S, Escoffier J, Abi Nahed R, Pierre V, Karaouzene T, Ray PF, et al. (2015) Dynamics of Sun5 Localization during Spermatogenesis in Wild Type and Dpy19l2 Knock-Out Mice Indicates That Sun5 Is Not Involved in Acrosome Attachment ...
متن کاملDynamics of Sun5 Localization during Spermatogenesis in Wild Type and Dpy19l2 Knock-Out Mice Indicates That Sun5 Is Not Involved in Acrosome Attachment to the Nuclear Envelope
The acrosome is an organelle that is central to sperm physiology and a defective acrosome biogenesis leads to globozoospermia, a severe male infertility. The identification of the actors involved in acrosome biogenesis is therefore particularly important to decipher the molecular pathogeny of globozoospermia. We recently showed that a defect in the DPY19L2 gene is present in more than 70% of gl...
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Using extracellular single-unit recordings, we have determined the characteristics of neurons in the ventral tuberomammillary nucleus (VTM) of wild-type (WT) and histidine decarboxylase knock-out (HDC-KO) mice during the sleep-waking cycle. The VTM neurons of HDC-KO mice showed no histamine immunoreactivity, but were immunoreactive for the histaminergic (HA) neuron markers adenosine deaminase a...
متن کاملEvaluation of aortic distensibility in wild type and ApoE-knock-out mice at 9.4 T
Material and Methods C57/BL6 and ApoE-/mice (n=6 per group) were evaluated using a horizontal bore 9.4 T MRI animal scanner (Bruker, Karlsruhe, Germany) with a dedicated 2x2 phased-array surface coil. All MRI experiments were performed during general anesthesia using a mixture of isoflurane (2%) and oxygene (98%) applied by a mask covering nose and mouth of the animals. For cine imaging of the ...
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ژورنال
عنوان ژورنال: Basic and Clinical Andrology
سال: 2013
ISSN: 2051-4190
DOI: 10.1186/2051-4190-23-7